![]() ![]() calcium/magnesium/potassium/sodium oxybatesĬodeine, calcium/magnesium/potassium/sodium oxybates.Either increases effects of the other by pharmacodynamic synergism.Comment: Mixed opiate agonist/antagonists usually produce additive sedation with narcotics however, in narcotic addicted pts., the antagonist activity may provoke withdrawal Sx. Comment: Mixed opiate agonist/antagonists usually produce additive sedation with narcotics however, in narcotic addicted pts., the antagonist activity may provoke withdrawal Sx.īutorphanol, codeine. Comment: Mixed opiate agonist/antagonists usually produce additive sedation with narcotics however, in narcotic addicted pts., the antagonist activity may provoke withdrawal Sx.īuprenorphine buccal, codeine. Interactions listed are representative examples and do not include all possible clinical examples.īuprenorphine, codeine. Avoid use when taking any oral drug that is dependent on threshold concentrations for efficacy. Bremelanotide may slow gastric emptying and potentially reduces the rate and extent of absorption of concomitantly administered oral medications. Monitor closely for signs of respiratory depression and sedation.īremelanotide will decrease the level or effect of codeine by Other (see comment). Limit dosages and durations to the minimum required. Reserve concomitant prescribing of these drugs in patients for whom other treatment options are inadequate. Profound sedation, respiratory depression, coma, and death may result if coadministered. Benzhydrocodone/acetaminophen, codeine.Either increases toxicity of the other by pharmacodynamic synergism. ![]()
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